Expression analysis of mitotic spindle checkpoint genes in breast carcinoma: role of NDC80/HEC1 in early breast tumorigenicity, and a two-gene signature for aneuploidy

BACKGROUND: Aneuploidy and chromosomal instability (CIN) are common abnormalities in human cancer. Alterations of the mitotic spindle checkpoint are likely to contribute to these phenotypes, but little is known about somatic alterations of mitotic spindle checkpoint genes in breast cancer. METHODS:...

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Detalhes bibliográficos
Main Authors: Bièche, Ivan, Vacher, Sophie, Lallemand, François, Tozlu-Kara, Sengül, Bennani, Hind, Beuzelin, Michèle, Driouch, Keltouma, Rouleau, Etienne, Lerebours, Florence, Ripoche, Hugues, Cizeron-Clairac, Géraldine, Spyratos, Frédérique, Lidereau, Rosette
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058099/
https://ncbi.nlm.nih.gov/pubmed/21352579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-10-23
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