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Silencing Early Viral Replication in Macrophages and Dendritic Cells Effectively Suppresses Flavivirus Encephalitis

West Nile (WN) and St. Louis encephalitis (SLE) viruses can cause fatal neurological infection and currently there is neither a specific treatment nor an approved vaccine for these infections. In our earlier studies, we have reported that siRNAs can be developed as broad-spectrum antivirals for the...

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Détails bibliographiques
Auteurs principaux: Ye, Chunting, Abraham, Sojan, Wu, Haoquan, Shankar, Premlata, Manjunath, N.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057999/
https://ncbi.nlm.nih.gov/pubmed/21423625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017889
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