The histone variant macroH2A suppresses melanoma progression through regulation of CDK8

Cancer is a disease consisting of both genetic and epigenetic changes. While increasing evidence demonstrates that tumour progression entails chromatin-mediated changes such as DNA methylation, the role of histone variants in cancer initiation and progression currently remains unclear. Here, we repo...

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Detalhes bibliográficos
Main Authors: Kapoor, Avnish, Goldberg, Matthew S., Cumberland, Lara K., Ratnakumar, Kajan, Segura, Miguel F., Emanuel, Patrick O., Menendez, Silvia, Vardabasso, Chiara, LeRoy, Gary, Vidal, Claudia I., Polsky, David, Osman, Iman, Garcia, Benjamin A., Hernando, Eva, Bernstein, Emily
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057940/
https://ncbi.nlm.nih.gov/pubmed/21179167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09590
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