ATRX-mediated chromatin association of histone variant macroH2A1 regulates α-globin expression

The histone variant macroH2A generally associates with transcriptionally inert chromatin; however, the factors that regulate its chromatin incorporation remain elusive. Here, we identify the SWI/SNF helicase ATRX (α-thalassemia/MR, X-linked) as a novel macroH2A-interacting protein. Unlike its role i...

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Detalhes bibliográficos
Principais autores: Ratnakumar, Kajan, Duarte, Luis F., LeRoy, Gary, Hasson, Dan, Smeets, Daniel, Vardabasso, Chiara, Bönisch, Clemens, Zeng, Tianying, Xiang, Bin, Zhang, David Y., Li, Haitao, Wang, Xiaowo, Hake, Sandra B., Schermelleh, Lothar, Garcia, Benjamin A., Bernstein, Emily
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2012
Assuntos:
Research Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3305981/
https://ncbi.nlm.nih.gov/pubmed/22391447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.179416.111
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