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Short Double-stranded RNAs with an Overhanging 5′ ppp-Nucleotide, as Found in Arenavirus Genomes, Act as RIG-I Decoys

Arenavirus RNA genomes are initiated by a “prime and realign” mechanism, such that the initiating GTP is found as a single unpaired (overhanging) nucleotide when the complementary genome ends anneal to form double-stranded (ds) RNA panhandle structures. dsRNAs modeled on these structures do not indu...

詳細記述

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書誌詳細
主要な著者: Marq, Jean-Baptiste, Hausmann, Stéphane, Veillard, Nicolas, Kolakofsky, Daniel, Garcin, Dominique
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2011
主題:
RNA
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057789/
https://ncbi.nlm.nih.gov/pubmed/21159780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.186262
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