Competition for Microtubule-binding with Dual Expression of Tau Missense and Splice Isoforms
How tau mutations lead to neurodegeneration is unknown but may be related to altered microtubule binding properties of mutant tau protein. The tendency for the mutations to cluster around the microtubule-binding domain of tau or to alter the ratios of those splice isoforms that affect binding suppor...
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| Publicado no: | Mol Biol Cell |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Cell Biology
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC30576/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11160831/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.12.1.171 |
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