Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease.

Apolipoprotein E (apoE), a plasma apolipoprotein that plays a central role in lipoprotein metabolism, is localized in the senile plaques, congophilic angiopathy, and neurofibrillary tangles of Alzheimer disease. Late-onset familial and sporadic Alzheimer disease patients have an increased frequency...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Strittmatter, W J, Weisgraber, K H, Huang, D Y, Dong, L M, Salvesen, G S, Pericak-Vance, M, Schmechel, D, Saunders, A M, Goldgaber, D, Roses, A D
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47295/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8367470/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.17.8098
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