Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease.

Amyloid beta-peptide (A beta) deposition in senile plaques and cerebral vessels is a neuropathological feature of Alzheimer disease (AD). We examined the possibility that commonly observed variability in A beta deposition in late-onset AD might be related to apolipoprotein E genotype (APOE gene; the...

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Hauptverfasser: Schmechel, D E, Saunders, A M, Strittmatter, W J, Crain, B J, Hulette, C M, Joo, S H, Pericak-Vance, M A, Goldgaber, D, Roses, A D
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1993
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC47627/
https://ncbi.nlm.nih.gov/pubmed/8415756
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