Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease.

Amyloid beta-peptide (A beta) deposition in senile plaques and cerebral vessels is a neuropathological feature of Alzheimer disease (AD). We examined the possibility that commonly observed variability in A beta deposition in late-onset AD might be related to apolipoprotein E genotype (APOE gene; the...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Schmechel, D E, Saunders, A M, Strittmatter, W J, Crain, B J, Hulette, C M, Joo, S H, Pericak-Vance, M A, Goldgaber, D, Roses, A D
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47627/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8415756/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.20.9649
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