A Critical Role for Neurofascin in Regulating Action Potential Initiation through Maintenance of the Axon Initial Segment

The axon initial segment (AIS) is critical for the initiation and propagation of action potentials. Assembly of the AIS requires interactions between scaffolding molecules and voltage-gated sodium channels, but the molecular mechanisms that stabilize the AIS are poorly understood. The neuronal isofo...

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Detalhes bibliográficos
Main Authors: Zonta, Barbara, Desmazieres, Anne, Rinaldi, Arianna, Tait, Steven, Sherman, Diane L., Nolan, Matthew F., Brophy, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057015/
https://ncbi.nlm.nih.gov/pubmed/21382554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2011.02.021
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