A Critical Role for Neurofascin in Regulating Action Potential Initiation through Maintenance of the Axon Initial Segment

The axon initial segment (AIS) is critical for the initiation and propagation of action potentials. Assembly of the AIS requires interactions between scaffolding molecules and voltage-gated sodium channels, but the molecular mechanisms that stabilize the AIS are poorly understood. The neuronal isofo...

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Main Authors: Zonta, Barbara, Desmazieres, Anne, Rinaldi, Arianna, Tait, Steven, Sherman, Diane L., Nolan, Matthew F., Brophy, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado: Cell Press 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057015/
https://ncbi.nlm.nih.gov/pubmed/21382554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2011.02.021
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