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Neurofascin and Kv7.3 are delivered to somatic and axon terminal surface membranes en route to the axon initial segment

Ion channel complexes promote action potential initiation at the mammalian axon initial segment (AIS), and modulation of AIS size by recruitment or loss of proteins can influence neuron excitability. Although endocytosis contributes to AIS turnover, how membrane proteins traffic to this proximal axo...

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Pubblicato in:eLife
Autori principali: Ghosh, Aniket, Malavasi, Elise LV, Sherman, Diane L, Brophy, Peter J
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7511229/
https://ncbi.nlm.nih.gov/pubmed/32903174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.60619
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