Differential Stability of PNS and CNS Nodal Complexes When Neuronal Neurofascin Is Lost

Fast, saltatory conduction in myelinated nerves requires the clustering of voltage-gated sodium channels (Nav) at nodes of Ranvier in a nodal complex. The Neurofascin (Nfasc) gene encodes neuronal Neurofascin 186 (Nfasc186) at the node and glial Neurofascin 155 at the paranode, and these proteins pl...

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Detalhes bibliográficos
Main Authors: Desmazieres, Anne, Zonta, Barbara, Zhang, Ao, Wu, Lai-Man N., Sherman, Diane L., Brophy, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2014
Assuntos:
Brief Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3983793/
https://ncbi.nlm.nih.gov/pubmed/24719087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4662-13.2014
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