Glial and neuronal isoforms of Neurofascin have distinct roles in the assembly of nodes of Ranvier in the central nervous system

Rapid nerve impulse conduction in myelinated axons requires the concentration of voltage-gated sodium channels at nodes of Ranvier. Myelin-forming oligodendrocytes in the central nervous system (CNS) induce the clustering of sodium channels into nodal complexes flanked by paranodal axoglial junction...

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Bibliographic Details
Main Authors: Zonta, Barbara, Tait, Steven, Melrose, Shona, Anderson, Heather, Harroch, Sheila, Higginson, Jennifer, Sherman, Diane L., Brophy, Peter J.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2008
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2442198/
https://ncbi.nlm.nih.gov/pubmed/18573915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200712154
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