TCRα enhancer activation occurs via a conformational change of a pre-assembled nucleo-protein complex
The TCR α enhancer (Eα) has served as a paradigm for studying how enhancers organize trans-activators into nucleo-protein complexes thought to recruit and synergistically stimulate the transcriptional machinery. Little is known, however, of either the extent or dynamics of Eα occupancy by nuclear fa...
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| Pubblicato in: | EMBO J |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2000
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305700/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10790370/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.9.2034 |
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