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TCRα enhancer activation occurs via a conformational change of a pre-assembled nucleo-protein complex
The TCR α enhancer (Eα) has served as a paradigm for studying how enhancers organize trans-activators into nucleo-protein complexes thought to recruit and synergistically stimulate the transcriptional machinery. Little is known, however, of either the extent or dynamics of Eα occupancy by nuclear fa...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC305700/ https://ncbi.nlm.nih.gov/pubmed/10790370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.9.2034 |
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