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Signal Peptides and Trans-membrane Regions are Broadly Immunogenic and have High CD8+ T Cell Epitope Densities: Implications for Vaccine Development
Cell mediated immune response has a major role in controlling the elimination of infectious agents. The rational design of sub-unit peptide vaccines against intracellular pathogens or cancer requires the use of antigenic sequence/s that can induce highly potent, long lasting and antigen-specific res...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3056897/ https://ncbi.nlm.nih.gov/pubmed/21316766 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2011.01.006 |
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