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Human self protein CD8+ T cell epitopes are both positively and negatively selected

The cellular immune system recognizes self epitopes in the context of MHC-I molecules. The immunological general view presumes that these self epitopes are just a background, both positively and negatively selecting T cells. We here estimate the number of epitopes in each human protein for many freq...

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Main Authors: almani, Michal, Raffaeli, Shai, Vider-Shalit, Tal, Tsaban, Lea, Fishbain, Vered, Louzoun, Yoram
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730470/
https://ncbi.nlm.nih.gov/pubmed/19291702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200838353
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