WT1 Synonymous Single Nucleotide Polymorphism rs16754 Correlates With Higher mRNA Expression and Predicts Significantly Improved Outcome in Favorable-Risk Pediatric Acute Myeloid Leukemia: A Report From the Children's Oncology Group

PURPOSE: To analyze the prevalence and clinical implications of Wilms' tumor 1 (WT1) single nucleotide polymorphism (SNP) rs16754 in the context of other prognostic markers in pediatric acute myeloid leukemia (AML). PATIENTS AND METHODS: Available diagnostic marrow specimens (n = 790) from 1,32...

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Autors principals: Ho, Phoenix A., Kuhn, Julia, Gerbing, Robert B., Pollard, Jessica A., Zeng, Rong, Miller, Kristen L., Heerema, Nyla A., Raimondi, Susana C., Hirsch, Betsy A., Franklin, Janet L., Lange, Beverly, Gamis, Alan S., Alonzo, Todd A., Meshinchi, Soheil
Format: Artigo
Idioma:Inglês
Publicat: American Society of Clinical Oncology 2011
Matèries:
Original Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056655/
https://ncbi.nlm.nih.gov/pubmed/21189390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2010.31.9327
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