WT1 Synonymous Single Nucleotide Polymorphism rs16754 Correlates With Higher mRNA Expression and Predicts Significantly Improved Outcome in Favorable-Risk Pediatric Acute Myeloid Leukemia: A Report From the Children's Oncology Group

PURPOSE: To analyze the prevalence and clinical implications of Wilms' tumor 1 (WT1) single nucleotide polymorphism (SNP) rs16754 in the context of other prognostic markers in pediatric acute myeloid leukemia (AML). PATIENTS AND METHODS: Available diagnostic marrow specimens (n = 790) from 1,32...

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Detalhes bibliográficos
Main Authors: Ho, Phoenix A., Kuhn, Julia, Gerbing, Robert B., Pollard, Jessica A., Zeng, Rong, Miller, Kristen L., Heerema, Nyla A., Raimondi, Susana C., Hirsch, Betsy A., Franklin, Janet L., Lange, Beverly, Gamis, Alan S., Alonzo, Todd A., Meshinchi, Soheil
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2011
Assuntos:
Original Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056655/
https://ncbi.nlm.nih.gov/pubmed/21189390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2010.31.9327
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