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Synthesis of Peptidomimetic Conjugates of Acyclic Nucleoside Phosphonates
Cyclic nucleoside phosphonates connected through a P-O-C linkage to a promoiety represent a class of prodrugs designed to overcome the low oral bioavailability of parent antiviral acyclic nucleoside phosphonates. In our prodrug approach, a non-toxic promoiety such as an amino acid or dipeptide is co...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3056568/ https://ncbi.nlm.nih.gov/pubmed/21154529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/0471142700.nc1504s43 |
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