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Value of General Acid–Base Catalysis to Ribonuclease A
Bovine pancreatic ribonuclease A (RNase A) is a much studied enzyme that efficiently catalyzes the cleavage of RNA. The active site of RNase A contains two histidine residues with imidazole groups positioned to act as a general base (H12) and a general acid (H119) during catalysis of RNA cleavage. R...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1994
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3056461/ https://ncbi.nlm.nih.gov/pubmed/21391696 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja00091a060 |
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