The Drosophila caspase DRONC is regulated by DIAP1

We have isolated the recently identified Drosophila caspase DRONC through its interaction with the effector caspase drICE. Ectopic expression of DRONC induces cell death in Schizosaccharomyces pombe, mammalian fibroblasts and the developing Drosophila eye. The caspase inhibitor p35 fails to rescue D...

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Bibliographic Details
Published in:EMBO J
Main Authors: Meier, Pascal, Silke, John, Leevers, Sally J., Evan, Gerard I.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2000
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Articles
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305598/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10675329/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.4.598
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