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The Drosophila caspase DRONC is regulated by DIAP1

We have isolated the recently identified Drosophila caspase DRONC through its interaction with the effector caspase drICE. Ectopic expression of DRONC induces cell death in Schizosaccharomyces pombe, mammalian fibroblasts and the developing Drosophila eye. The caspase inhibitor p35 fails to rescue D...

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Détails bibliographiques
Auteurs principaux: Meier, Pascal, Silke, John, Leevers, Sally J., Evan, Gerard I.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2000
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC305598/
https://ncbi.nlm.nih.gov/pubmed/10675329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.4.598
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