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The Drosophila caspase DRONC is regulated by DIAP1

We have isolated the recently identified Drosophila caspase DRONC through its interaction with the effector caspase drICE. Ectopic expression of DRONC induces cell death in Schizosaccharomyces pombe, mammalian fibroblasts and the developing Drosophila eye. The caspase inhibitor p35 fails to rescue D...

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Détails bibliographiques
Publié dans:EMBO J
Auteurs principaux: Meier, Pascal, Silke, John, Leevers, Sally J., Evan, Gerard I.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2000
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305598/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10675329/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.4.598
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