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IAP-antagonists exhibit non-redundant modes of action through differential DIAP1 binding
The Drosophila inhibitor of apoptosis protein DIAP1 ensures cell viability by directly inhibiting caspases. In cells destined to die this IAP-mediated inhibition of caspases is overcome by IAP-antagonists. Genetic evidence indicates that IAP-antagonists are non-equivalent and function synergisticall...
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| 發表在: | EMBO J |
|---|---|
| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group
2003
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC291812/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14657035/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg617 |
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