IAP-antagonists exhibit non-redundant modes of action through differential DIAP1 binding
The Drosophila inhibitor of apoptosis protein DIAP1 ensures cell viability by directly inhibiting caspases. In cells destined to die this IAP-mediated inhibition of caspases is overcome by IAP-antagonists. Genetic evidence indicates that IAP-antagonists are non-equivalent and function synergisticall...
Guardat en:
| Publicat a: | EMBO J |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2003
|
| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC291812/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14657035/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg617 |
| Etiquetes: |
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|
