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Jafrac2 is an IAP antagonist that promotes cell death by liberating Dronc from DIAP1
Members of the Inhibitor of Apoptosis Protein (IAP) family are essential for cell survival in Drosophila and appear to neutralize the cell death machinery by binding to and ubiquitylating pro-apoptotic caspases. Cell death is triggered when ‘Reaper-like’ proteins bind to IAPs and liberate caspases f...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2002
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC129052/ https://ncbi.nlm.nih.gov/pubmed/12356728 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf530 |
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