Activation of Rho through a cross-link with polyamines catalyzed by Bordetella dermonecrotizing toxin

The small GTPase Rho, which regulates a variety of cell functions, also serves as a specific substrate for bacterial toxins. Here we demonstrate that Bordetella dermonecrotizing toxin (DNT) catalyzes cross-linking of Rho with ubiquitous polyamines such as putrescine, spermidine and spermine. Mass sp...

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Bibliographic Details

Published in:	EMBO J
Main Authors:	Masuda, Minako, Betancourt, Lazaro, Matsuzawa, Takeshi, Kashimoto, Takashige, Takao, Toshifumi, Shimonishi, Yasutsugu, Horiguchi, Yasuhiko
Format:	Artigo
Language:	Inglês
Published:	Nature Publishing Group 2000
Subjects:	Articles
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305590/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10675321/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.4.521
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