In Vivo Modifications of Small GTPase Rac and Cdc42 by Bordetella Dermonecrotic Toxin

Bordetella dermonecrotic toxin (DNT) is known to activate the small GTPase Rho through deamidation or polyamination. In this study, we examined whether Rac and Cdc42, the two other members of the Rho family, serve as intracellular targets for the toxin. Immunoprecipitation and immunoblot assays reve...

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Main Authors: Masuda, Minako, Minami, Masayoshi, Shime, Hiroaki, Matsuzawa, Takeshi, Horiguchi, Yasuhiko
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2002
Teme:
Molecular Pathogenesis
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC127728/
https://ncbi.nlm.nih.gov/pubmed/11796639
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