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Activation of Rho through a cross-link with polyamines catalyzed by Bordetella dermonecrotizing toxin

The small GTPase Rho, which regulates a variety of cell functions, also serves as a specific substrate for bacterial toxins. Here we demonstrate that Bordetella dermonecrotizing toxin (DNT) catalyzes cross-linking of Rho with ubiquitous polyamines such as putrescine, spermidine and spermine. Mass sp...

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Bibliografski detalji
Glavni autori: Masuda, Minako, Betancourt, Lazaro, Matsuzawa, Takeshi, Kashimoto, Takashige, Takao, Toshifumi, Shimonishi, Yasutsugu, Horiguchi, Yasuhiko
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2000
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC305590/
https://ncbi.nlm.nih.gov/pubmed/10675321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.4.521
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