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Activation of Rho through a cross-link with polyamines catalyzed by Bordetella dermonecrotizing toxin
The small GTPase Rho, which regulates a variety of cell functions, also serves as a specific substrate for bacterial toxins. Here we demonstrate that Bordetella dermonecrotizing toxin (DNT) catalyzes cross-linking of Rho with ubiquitous polyamines such as putrescine, spermidine and spermine. Mass sp...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC305590/ https://ncbi.nlm.nih.gov/pubmed/10675321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.4.521 |
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