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Role of c-Cbl–Dependent Regulation of Phospholipase Cγ1 Activation in Experimental Choroidal Neovascularization

PURPOSE. Activation of phospholipase Cγ1 (PLCγ1) by vascular endothelial growth factor receptor (VEGFR)-2 is necessary for proliferation and tube formation of endothelial cells in vitro. Previous work has demonstrated that Casitas B-lineage lymphoma (c-Cbl) promotes ubiquitination of PLCγ1 and suppr...

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Bibliografski detalji
Glavni autori: Husain, Deeba, Meyer, Rosana D., Mehta, Manisha, Pfeifer, Walther M., Chou, Eva, Navruzbekov, Gregory, Ahmed, Ednan, Rahimi, Nader
Format: Artigo
Jezik:Inglês
Izdano: Association for Research in Vision and Ophthalmology, Inc. 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055779/
https://ncbi.nlm.nih.gov/pubmed/20592236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-5255
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