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Altered Expression of Retinal Molecular Markers in the Canine RPE65 Model of Leber Congenital Amaurosis

PURPOSE. Leber congenital amaurosis (LCA) is a group of childhood-onset retinal diseases characterized by severe visual impairment or blindness. One form is caused by mutations in the RPE65 gene, which encodes the retinal pigment epithelium (RPE) isomerase. In this study, the retinal structure and e...

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Hlavní autoři: Hernández, Maria, Pearce-Kelling, Susan E., Rodriguez, F. David, Aguirre, Gustavo D., Vecino, Elena
Médium: Artigo
Jazyk:Inglês
Vydáno: Association for Research in Vision and Ophthalmology, Inc. 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055778/
https://ncbi.nlm.nih.gov/pubmed/20671290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-5213
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