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Variation in Nicotinic Acetylcholine Receptor Genes is Associated with Multiple Substance Dependence Phenotypes

There is shared genetic risk for dependence on multiple substances, and the nicotinic receptor gene cluster on chromosome 15 harbors multiple polymorphisms that associate to this risk. Here, we report the results of an association study with 21 SNPs genotyped across the CHRNA5, CHRNA3, and CHRNB4 lo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sherva, Richard, Kranzler, Henry R, Yu, Yi, Logue, Mark W, Poling, James, Arias, Albert J, Anton, Raymond F, Oslin, David, Farrer, Lindsay A, Gelernter, Joel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055642/
https://ncbi.nlm.nih.gov/pubmed/20485328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2010.64
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