Childhood Adversity Increases Risk for Nicotine Dependence and Interacts with α5 Nicotinic Acetylcholine Receptor Genotype Specifically in Males

The relative importance of specific genetic and environmental factors in regulating nicotine dependence (ND) risk, including the effects on specific forms of childhood adversity on smoking risk, have been understudied. Genome-wide association studies and rodent models have demonstrated that the α5 n...

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Main Authors: Xie, Pingxing, Kranzler, Henry R, Zhang, Huiping, Oslin, David, Anton, Raymond F, Farrer, Lindsay A, Gelernter, Joel
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2012
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260970/
https://ncbi.nlm.nih.gov/pubmed/22012472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2011.240
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