Variation in the Nicotinic Acetylcholine Receptor Gene Cluster CHRNA5–CHRNA3–CHRNB4 and Its Interaction with Recent Tobacco Use Influence Cognitive Flexibility

Variants in the CHRNA5–CHRNA3–CHRNB4 gene cluster have been associated with nicotine dependence (ND) and ND-related traits. To evaluate a potential underlying mechanism for this association, we investigated the effects of 10 variants in this gene cluster and their interactive effects as a result of...

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Detalhes bibliográficos
Main Authors: Zhang, Huiping, Kranzler, Henry R, Poling, James, Gelernter, Joel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055317/
https://ncbi.nlm.nih.gov/pubmed/20631687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2010.95
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