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Regulation of c–myc expression by IFN–γ through Stat1-dependent and -independent pathways
Interferons (IFNs) inhibit cell growth in a Stat1-dependent fashion that involves regulation of c–myc expression. IFN–γ suppresses c–myc in wild-type mouse embryo fibroblasts, but not in Stat1-null cells, where IFNs induce c–myc mRNA rapidly and transiently, thus revealing a novel signaling pathway....
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2000
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC305560/ https://ncbi.nlm.nih.gov/pubmed/10637230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.2.263 |
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