Inflammatory impact of IFN-γ in CD8(+) T cell-mediated lung injury is mediated by both Stat1-dependent and -independent pathways

Influenza infection results in considerable pulmonary pathology, a significant component of which is mediated by CD8(+) T cell effector functions. To isolate the specific contribution of CD8(+) T cells to lung immunopathology, we utilized a nonviral murine model in which alveolar epithelial cells ex...

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Argitaratua izan da:Am J Physiol Lung Cell Mol Physiol
Egile Nagusiak: Ramana, Chilakamarti V., DeBerge, Matthew P., Kumar, Aseem, Alia, Christopher S., Durbin, Joan E., Enelow, Richard I.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Physiological Society 2015
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Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4385989/
https://ncbi.nlm.nih.gov/pubmed/25617378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00360.2014
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