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Inflammatory impact of IFN-γ in CD8(+) T cell-mediated lung injury is mediated by both Stat1-dependent and -independent pathways
Influenza infection results in considerable pulmonary pathology, a significant component of which is mediated by CD8(+) T cell effector functions. To isolate the specific contribution of CD8(+) T cells to lung immunopathology, we utilized a nonviral murine model in which alveolar epithelial cells ex...
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Publicado en: | Am J Physiol Lung Cell Mol Physiol |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado: |
American Physiological Society
2015
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Assuntos: | |
Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4385989/ https://ncbi.nlm.nih.gov/pubmed/25617378 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00360.2014 |
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