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Constitutive and IFN-γ-induced nuclear import of STAT1 proceed through independent pathways
STAT1 functions as both a constitutive transcriptional regulator and, in response to cytokine stimulation of cells, as an inducible tyrosine-phosphorylated transcription factor. Here, we identify and characterize a non-transferable nuclear targeting sequence in the STAT1 DNA-binding domain. This con...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125830/ https://ncbi.nlm.nih.gov/pubmed/11823427 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.3.344 |
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