Rosiglitazone Rescues Memory Impairment in Alzheimer's Transgenic Mice: Mechanisms Involving a Reduced Amyloid and Tau Pathology

Clinical studies suggest that agonists at peroxisome proliferator-activated receptor gamma (PPARγ) may exert beneficial effects in patients with mild-to-moderate Alzheimer's disease (AD), but the mechanism for the potential therapeutic interest of this class of drugs has not yet been elucidated...

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Autors principals: Escribano, Luis, Simón, Ana-María, Gimeno, Esther, Cuadrado-Tejedor, Mar, López de Maturana, Rakel, García-Osta, Ana, Ricobaraza, Ana, Pérez-Mediavilla, Alberto, Del Río, Joaquín, Frechilla, Diana
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2010
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055461/
https://ncbi.nlm.nih.gov/pubmed/20336061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2010.32
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