TrkB/BDNF-Dependent Striatal Plasticity and Behavior in a Genetic Model of Epilepsy: Modulation by Valproic Acid

In mice lacking the central domain of the presynaptic scaffold Bassoon the occurrence of repeated cortical seizures induces cell-type-specific plasticity changes resulting in a general enhancement of the feedforward inhibition within the striatal microcircuit. Early antiepileptic treatment with valp...

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Autores principales: Ghiglieri, Veronica, Sgobio, Carmelo, Patassini, Stefano, Bagetta, Vincenza, Fejtova, Anna, Giampà, Carmela, Marinucci, Silvia, Heyden, Alexandra, Gundelfinger, Eckart D, Fusco, Francesca R, Calabresi, Paolo, Picconi, Barbara
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2010
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055450/
https://ncbi.nlm.nih.gov/pubmed/20200504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2010.23
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