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Squamocin modulates histone H3 phosphorylation levels and induces G(1 )phase arrest and apoptosis in cancer cells
BACKGROUND: Histone modifications in tumorigenesis are increasingly recognized as important epigenetic factors leading to cancer. Increased phosphorylation levels of histone H3 as a result of aurora B and pMSK1 overexpression were observed in various tumors. We selected aurora B and MSK1 as represen...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3055232/ https://ncbi.nlm.nih.gov/pubmed/21299907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-58 |
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