Pterostilbene Simultaneously Induced G0/G1-Phase Arrest and MAPK-Mediated Mitochondrial-Derived Apoptosis in Human Acute Myeloid Leukemia Cell Lines

BACKGROUND: Pterostilbene (PTER) is a dimethylated analog of the phenolic phytoalexin, resveratrol, with higher anticancer activity in various tumors. Herein, the molecular mechanisms by which PTER exerts its anticancer effects against acute myeloid leukemia (AML) cells were investigated. METHODOLOG...

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Detalhes bibliográficos
Principais autores: Hsiao, Pei-Ching, Chou, Ying-Erh, Tan, Peng, Lee, Wei-Jiunn, Yang, Shun-Fa, Chow, Jyh-Ming, Chen, Hui-Yu, Lin, Chien-Huang, Lee, Liang-Ming, Chien, Ming-Hsien
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140770/
https://ncbi.nlm.nih.gov/pubmed/25144448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105342
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