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Sinularin induces DNA damage, G2/M phase arrest, and apoptosis in human hepatocellular carcinoma cells

BACKGROUND: Sinularin isolated from the cultured soft coral Sinularia flexibilis has been reported to exert potent cytotoxic effects against particular types of cancer. This study was carried out to investigate the cytotoxic effects in sinularin-treated human hepatocellular carcinoma cells, HepG2, a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:BMC Complement Altern Med
Hauptverfasser: Chung, Ting-Wen, Lin, Shih-Chao, Su, Jui-Hsin, Chen, Yu-Kuo, Lin, Chi-Chien, Chan, Hong-Lin
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5248443/
https://ncbi.nlm.nih.gov/pubmed/28103869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12906-017-1583-9
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