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Sinularin induces DNA damage, G2/M phase arrest, and apoptosis in human hepatocellular carcinoma cells

BACKGROUND: Sinularin isolated from the cultured soft coral Sinularia flexibilis has been reported to exert potent cytotoxic effects against particular types of cancer. This study was carried out to investigate the cytotoxic effects in sinularin-treated human hepatocellular carcinoma cells, HepG2, a...

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Detalhes bibliográficos
Publicado no:BMC Complement Altern Med
Principais autores: Chung, Ting-Wen, Lin, Shih-Chao, Su, Jui-Hsin, Chen, Yu-Kuo, Lin, Chi-Chien, Chan, Hong-Lin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5248443/
https://ncbi.nlm.nih.gov/pubmed/28103869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12906-017-1583-9
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