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Life or death: p53-induced apoptosis requires DNA binding cooperativity

The tumor suppressor p53 provides exquisite protection from cancer by balancing cell survival and death in response to stress. Sustained stress or irreparable damage trigger p53's killer functions to permanently eliminate genetically-altered cells as a potential source of cancer. To prevent the...

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Hlavní autoři: Schlereth, Katharina, Charles, Joël P, Bretz, Anne C, Stiewe, Thorsten
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055192/
https://ncbi.nlm.nih.gov/pubmed/20948308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.9.20.13595
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