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Life or death: p53-induced apoptosis requires DNA binding cooperativity

The tumor suppressor p53 provides exquisite protection from cancer by balancing cell survival and death in response to stress. Sustained stress or irreparable damage trigger p53's killer functions to permanently eliminate genetically-altered cells as a potential source of cancer. To prevent the...

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Detalhes bibliográficos
Main Authors: Schlereth, Katharina, Charles, Joël P, Bretz, Anne C, Stiewe, Thorsten
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055192/
https://ncbi.nlm.nih.gov/pubmed/20948308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.9.20.13595
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