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Life or death: p53-induced apoptosis requires DNA binding cooperativity

The tumor suppressor p53 provides exquisite protection from cancer by balancing cell survival and death in response to stress. Sustained stress or irreparable damage trigger p53's killer functions to permanently eliminate genetically-altered cells as a potential source of cancer. To prevent the...

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Bibliografiska uppgifter
Huvudupphovsmän: Schlereth, Katharina, Charles, Joël P, Bretz, Anne C, Stiewe, Thorsten
Materialtyp: Artigo
Språk:Inglês
Publicerad: Landes Bioscience 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055192/
https://ncbi.nlm.nih.gov/pubmed/20948308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.9.20.13595
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