Characterization of the p53 Cistrome – DNA Binding Cooperativity Dissects p53's Tumor Suppressor Functions

p53 protects us from cancer by transcriptionally regulating tumor suppressive programs designed to either prevent the development or clonal expansion of malignant cells. How p53 selects target genes in the genome in a context- and tissue-specific manner remains largely obscure. There is growing evid...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Schlereth, Katharina, Heyl, Charlotte, Krampitz, Anna-Maria, Mernberger, Marco, Finkernagel, Florian, Scharfe, Maren, Jarek, Michael, Leich, Ellen, Rosenwald, Andreas, Stiewe, Thorsten
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744428/
https://ncbi.nlm.nih.gov/pubmed/23966881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003726
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados