Histone deacetylase (HDAC) inhibitors attenuate cardiac hypertrophy by suppressing autophagy

Histone deacetylases (HDACs) regulate cardiac plasticity; however, their molecular targets are unknown. As autophagy contributes to pathological cardiac remodeling, we hypothesized that HDAC inhibitors target autophagy. The prototypical HDAC inhibitor (HDACi), trichostatin A (TSA), attenuated both l...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Cao, Dian J., Wang, Zhao V., Battiprolu, Pavan K., Jiang, Nan, Morales, Cyndi R., Kong, Yongli, Rothermel, Beverly A., Gillette, Thomas G., Hill, Joseph A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2011
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3053983/
https://ncbi.nlm.nih.gov/pubmed/21367693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1015081108
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller