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Oxidative damage and TGF-β differentially induce lung epithelial cell sonic hedgehog and tenascin-C expression: implications for the regulation of lung remodelling in idiopathic interstitial lung disease

Idiopathic interstitial lung diseases (iILDs) are characterized by inflammation, hyperplasia of Type-II alveolar epithelial cells (AECs) and lung remodelling often with progressive fibrosis. It remains unclear which signals initiate iILD and/or maintain the disease processes. Using real-time RT-PCR...

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Detalhes bibliográficos
Principais autores: Fitch, Paul M, Howie, Sarah E M, Wallace, William A H
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3052752/
https://ncbi.nlm.nih.gov/pubmed/21039988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2613.2010.00743.x
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