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Epithelial heparan sulfate regulates Sonic Hedgehog signaling in lung development

The tree-like structure of the mammalian lung is generated from branching morphogenesis, a reiterative process that is precisely regulated by numerous factors. How the cell surface and extra cellular matrix (ECM) molecules regulate this process is still poorly understood. Herein, we show that epithe...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: He, Hua, Huang, Meina, Sun, Shenfei, Wu, Yihui, Lin, Xinhua
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5597256/
https://ncbi.nlm.nih.gov/pubmed/28859094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006992
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