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Epithelial heparan sulfate regulates Sonic Hedgehog signaling in lung development

The tree-like structure of the mammalian lung is generated from branching morphogenesis, a reiterative process that is precisely regulated by numerous factors. How the cell surface and extra cellular matrix (ECM) molecules regulate this process is still poorly understood. Herein, we show that epithe...

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Pubblicato in:PLoS Genet
Autori principali: He, Hua, Huang, Meina, Sun, Shenfei, Wu, Yihui, Lin, Xinhua
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5597256/
https://ncbi.nlm.nih.gov/pubmed/28859094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006992
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