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Sonic Hedgehog Opposes Epithelial Cell Cycle Arrest

Stratified epithelium displays an equilibrium between proliferation and cell cycle arrest, a balance that is disrupted in basal cell carcinoma (BCC). Sonic hedgehog (Shh) pathway activation appears sufficient to induce BCC, however, the way it does so is unknown. Shh-induced epidermal hyperplasia is...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Fan, Hongran, Khavari, Paul A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 1999
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2164980/
https://ncbi.nlm.nih.gov/pubmed/10508856
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