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The role of indoleamine 2,3-dioxygenase (IDO) in the pathophysiology of interferon-α-induced depression

The mechanisms by which administration of interferon-α induces neuropsychiatric side effects, such as depressive symptoms and changes in cognitive function, are not clear as yet. Direct influence on serotonergic neurotransmission may contribute to these side effects. In addition, the enzyme indoleam...

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Autori principali: Wichers, Marieke C., Maes, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC305266/
https://ncbi.nlm.nih.gov/pubmed/14719046
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