Association of a Polymorphism in the Indoleamine-2,3-Dioxygenase Gene and Interferon-α-Induced Depression in Patients with Chronic Hepatitis C

Interferon (IFN)-α treatment for infectious diseases and cancer is associated with significant depressive symptoms that can limit therapeutic efficacy. Multiple mechanisms have been implicated in IFN-α-induced depression including immune, neuroendocrine and neurotransmitter pathways. To further expl...

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Autors principals: Smith, Alicia K., Simon, Jason S., Gustafson, Eric L., Noviello, Stephanie, Cubells, Joseph F., Epstein, Michael P., Devlin, David J., Qiu, Ping, Albrecht, Janice K., Brass, Clifford A., Sulkowski, Mark S., McHutchinson, John G., Miller, Andrew H.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3179823/
https://ncbi.nlm.nih.gov/pubmed/21691274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2011.67
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